Table of Contents
Table of Contents 3
List of Tables 7
List of Figures 8
Mitsubishi Tanabe Pharma Corp, Pharmaceuticals & Healthcare, Deals By Year, 2012 to YTD 2018 9
Mitsubishi Tanabe Pharma Corp, Pharmaceuticals & Healthcare Deals By Type, 2012 to YTD 2018 10
Mitsubishi Tanabe Pharma Corp, Pharmaceuticals & Healthcare, Deals By Region, 2012 to YTD 2018 11
Mitsubishi Tanabe Pharma Corp, Pharmaceuticals & Healthcare, Deals By Therapy Area, 2012 to YTD 2018 12
Mitsubishi Tanabe Pharma Corp, Medical Devices Deals, 2012 to YTD 2018 14
Mitsubishi Tanabe Pharma Corp, Pharmaceuticals & Healthcare, Deals Summary, 2012 to YTD 2018 15
Mitsubishi Tanabe Pharma Corp, Pharmaceuticals & Healthcare, Deal Details 22
Venture Financing 22
QurAlis Raises Funds through Seed Financing 22
Ribometrix Raises USD7.5 Million in Seed Financing 23
Forge Therapeutics Raises USD15 million in Series A Financing 24
Rigontec Raises Additional USD16.7 Million in Series A Financing 25
miRagen Therapeutics Raises USD41 Million in Series C Financing 27
Thrasos Therapeutics Raises USD21 Million in Series D Financing 29
NeuroDerm Raises USD16 Million in Venture Financing 31
Covagen Raises US$50.3 Million In Series B Financing 32
F-Star Alpha Raises US$13 Million In Series A Financing 34
Thrasos Therapeutics Raises US$35 Million In Venture Financing 35
Genocea Biosciences Raises US$30 Million In Series C Financing 37
GenKyoTex Raises US$26 Million In Extended Series C Financing 39
Partnerships 41
Mitsubishi Tanabe Pharma and Osaka University Enter into Agreement 41
Mitsubishi Tanabe Pharma and Hitachi Enter into Agreement 42
Dyadic International Enters into Research Agreement with Mitsubishi Tanabe Pharma 43
AvantGen Partners with Tanabe Research Laboratories USA 44
Mitsubishi Tanabe Pharma, Order made Medical Research and Trans Chromosomics Form Partnership 45
Clinigen Enters into Distribution Agreement with Mitsubishi Tanabe Pharma 46
Mitsubishi Tanabe Pharma Forms Joint Venture with Research Foundation for Microbial Diseases of Osaka University 47
Mitsubishi Tanabe Pharma Expands Co-Promotion Agreement with Janssen Pharma 48
Takeda Pharma and Shionogi Enter into Research Agreement with Sumitomo Dainippon Pharma, Ono Pharma and Mitsubishi Tanabe Pharma 49
Mitsubishi Tanabe Pharma Enters into Research Agreement with Medicine for Malaria Venture 51
Teikoku Seiyaku Enters into Agreement with Mitsubishi Tanabe Pharma 52
Sun Pharma Enters into Distribution Agreement with Mitsubishi Tanabe Pharma 53
Mitsubishi Tanabe Pharma Enters into Distribution Agreement with Janssen Biotech 54
Akebia Therapeutics Enters into Agreement with Mitsubishi Tanabe Pharma 55
Medicago Enters into Contract with Public Health Agency of Canada 56
Regeneron Pharma Enters into Agreement with Mitsubishi Tanabe Pharma 57
Cardiome Pharma Enters into Agreement with Mitsubishi Tanabe Pharma Europe 58
Mitsubishi Tanabe Enters into Co-Promotion Agreement with Johnson & Johnson K.K. 59
Medicago Enters into Agreement with University of Cape Town 60
AstraZeneca Enters into Research Agreement with Mitsubishi Tanabe 61
AnGes MG Enters Into Co-Marketing Agreement With Mitsubishi Tanabe Pharma For Collategene 62
Medicago Enters Into Co-Development Agreement With A Global Pharma Company 63
Medicago Enters Into Co-Development Agreement With Mitsubishi Tanabe Pharma For Vaccines 64
Mitsubishi Tanabe Pharma Expands its Co-Marketing Agreement with Daiichi Sankyo for MP-513 And TA-7284 65
Medicago Enters Into Co-Development Agreement With Cellectis 66
Licensing Agreements 67
Aquestive Therapeutics Enters into Licensing Agreement with Mitsubishi Tanabe Pharma 67
Mitsubishi Tanabe Pharma to Terminate Licensing Agreement with Kolon Life Science 68
Menarini Enters into Licensing Agreement with Mitsubishi Tanabe Pharma for Spedra 69
Tanabe Research Labs Enters into a Licensing Agreement with MedImmune 70
AnGes Enters into Licensing Agreement with Mitsubishi Tanabe Pharma 71
Neurocrine Biosciences Enters into Licensing Agreement with Mitsubishi Tanabe Pharma 72
Covagen Enters Into Licensing Agreement With Mitsubishi Tanabe Pharma And Tanabe Research Labs 73
Medicago Enters Into Licensing Agreement With Philip Morris Products For Influenza Vaccines 75
Philip Morris Products Enters Into Licensing Agreement With Medicago For Protein Development Technologies 76
Nuron Biotech Enters Into Licensing Agreement With Mitsubishi Tanabe For HibTITER 77
Covagen Expands Licensing Agreement With Mitsubishi Tanabe Pharma And Tanabe Research Labs 78
Immune Design And Medicago Enter Into Licensing Agreement To Develop Influenza Vaccines 80
Dezima Pharma Enters Into Licensing Agreement With Mitsubishi Tanabe Pharma For DEZ-001 81
Equity Offering 82
miRagen Therapeutics Raises USD40.7 Million in Private Placement of Shares 82
NeuroDerm Completes Underwriters Exercise of Over-Allotment Option of Public Offering for USD86.3 Million 84
NeuroDerm Raises USD77 Million in Public Offering of Shares 86
NeuroDerm Raises USD45 Million in IPO 88
Medicago Announces Private Placement Of Common Stock For US$3.4 Million 90
Asset Transactions 91
Sawai Pharma to Acquire Kashima Plant from Mitsubishi Tanabe Pharma Factory for USD39.3 Million 91
Acquisition 92
Mitsubishi Tanabe Pharma Acquires Stelic Institute 92
Merck Acquires Rigontec 93
Mitsubishi Tanabe Pharma Acquires Neuroderm for USD1.1 Billion 95
Nipro Acquires Tanabe Seiyaku Hanbai from Mitsubishi Tanabe Pharma 97
CMIC Holdings Acquires Pharma Company from Mitsubishi Tanabe Pharma for USD32.2 Million 98
Medicago Completes Divestment Of 53.9% Stake To Mitsubishi Tanabe Pharma For US$ 172 Million In Going Private Transaction 99
Opko Health Completes Acquisition Of Cytochroma For Up To US$290 Million 101
Mitsubishi Tanabe To Acquire Remaining 49% Stake In Bipha From Nipro 103
Shire Completes Acquisition of Ferrokin Biosciences For Up To US$320 Million 104
Mitsubishi Tanabe Pharma Corp – Key Competitors 106
Mitsubishi Tanabe Pharma Corp – Key Employees 107
Mitsubishi Tanabe Pharma Corp – Locations And Subsidiaries 108
Head Office 108
Other Locations & Subsidiaries 108
Joint Venture 110
Recent Developments 112
Strategy And Business Planning 112
Sep 29, 2017: Mitsubishi Tanabe Pharma: Organizational Change and Personnel Change 112
Financial Announcements 113
Nov 01, 2017: Mitsubishi Tanabe Pharma: Financial Results for the First Six Months of the Fiscal year ending March 31, 2018 113
May 10, 2017: Mitsubishi Tanabe Pharma Reports Revenue Of JPY424 Billion In Fiscal 2017 115
Corporate Communications 116
Sep 28, 2018: New country manager brings significant business leadership and healthcare expertise to Mitsubishi Tanabe Pharma Canada 116
Government and Public Interest 117
Jul 02, 2018: Mitsubishi Tanabe Pharma: Open Call for Applicants for investigator-Initiated Clinical Research Funds 117
May 30, 2018: Notice Regarding Establishment of Immune-mediated Inflammatory Diseases Consortium for Drug Development 118
Product News 119
11/30/2017: Mitsubishi Tanabe Pharma America Announces Addition of RADICAVA (edaravone) to U.S. Department of Veterans Affairs National Formulary 119
11/16/2017: Mitsubishi Tanabe Pharma America Announces 1,000 People with ALS Have Received FDA-Approved Treatment Option in First Three Months Available 120
Oct 11, 2017: Astellas, Mitsubishi Tanabe Pharma, and Daiichi Sankyo Conduct “JOINUS,” a New Drug Discovery Program Using Drug-Repositioning Compound Library 121
08/11/2017: Allegheny General Hospital Patient Among First in U.S. to Receive New Drug for Treatment of ALS 122
08/08/2017: First FDA-Approved Treatment For ALS In 22 Years Now Available In U.S. 123
07/25/2017: MT Pharma America Begins Patient Insurance Benefits Investigation Process in Advance of Availability of RADICAVA 124
06/30/2017: MT Pharma America Enrolls More Than 700 Sites of Care in Newly Created National Infusion Center Directory for ALS Patients 125
06/20/2017: Fingolimod Hydrochloride wins Patent Infringement Lawsuit in the U.S. District Court 126
05/18/2017: MT Pharma America Presents 12-Month RADICAVA (Edaravone) and Amyotrophic Lateral Sclerosis Data at the European Network for the Cure of ALS (ENCALS) Annual Meeting 127
05/16/2017: Mitsubishi Tanabe Pharma announces The Lancet Neurology publication of the positive clinical results of Edaravone for ALS 128
05/05/2017: MT Pharma America Announces FDA Approval of RADICAVA (Edaravone), the First New Treatment Option for ALS in More Than 20 Years 129
04/24/2017: Novartis real-world data at AAN confirms benefit of Gilenya on four key measures of disease activity in relapsing MS 130
04/18/2018: Mitsubishi Tanabe Pharma America Announces ALS Presentations At American Academy Of Neurology Annual Meeting 132
02/21/2017: Minerva Neurosciences to Host R&D Day Focused on Unmet Needs and Emerging Treatment Strategies in Schizophrenia 133
Product Approvals 134
May 28, 2018: EMA accepts our filing for Edaravone to treat ALS 134
Apr 10, 2018: Health Canada Accepts Mitsubishi Tanabe Pharma’s NDS Filing for Edaravone to Treat ALS 135
Jan 23, 2018: Swissmedic accepts our filing for Edaravone to treat ALS 136
Dec 18, 2017: Novartis multiple sclerosis therapy fingolimod granted FDA Breakthrough Therapy designation for pediatric MS 137
Clinical Trials 138
Jun 21, 2018: Mitsubishi Tanabe Pharma America to Present Data on RADICAVA (edaravone) at the European Network for the Cure of ALS (ENCALS) Annual Meeting 138
Apr 09, 2018: Minerva Neurosciences Screens First Patient in Phase 2b Trial of MIN-117 to Treat Major Depressive Disorder 139
Dec 19, 2017: Minerva Neurosciences Screens First Patient in Phase 3 Trial Of MIN-101 to Treat Negative Symptoms in Schizophrenia 140
Dec 05, 2017: Mitsubishi Tanabe Pharma America to Present Data on RADICAVA (Edaravone) At 28th International Symposium on ALS/MND in Boston 141
Oct 28, 2017: Novartis PARADIGMS data show children and adolescents with MS had an 82% lower relapse rate with Gilenya vs. interferon beta-1a 142
Oct 25, 2017: Novartis confirms leadership in multiple sclerosis with scientific advancements and new data presented at ECTRIMS 144
Sep 07, 2017: Comprehensive Edaravone Clinical Program Data Published as Supplement to Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration Journal 145
Sep 05, 2017: Novartis landmark Phase III trial shows fingolimod significantly reduces relapses in children and adolescents with MS 146
Jul 31, 2017: American Journal of Psychiatry Publishes Minerva Neurosciences’ MIN-101 Phase 2b Trial Results for Treatment of Negative Symptoms in Schizophrenia 148
Jun 22, 2017: Minerva Announces Completion of Bridging Study to Select Improved Formulation of MIN-101 for Use in Phase 3 Trial for the Treatment of Negative Symptoms in Patients With Schizophrenia 149
May 15, 2017: Minerva Announces Outcome of End-of-Phase 2 Meeting With FDA 150
May 15, 2017: Minerva Provides Update on Phase 3 Design and Development Strategy for MIN-101 151
Apr 20, 2017: MT Pharma America to Present Data on Investigational Edaravone and Amyotrophic Lateral Sclerosis at the 2017 American Academy of Neurology Annual Meeting 153
Jan 20, 2017: Additional Data Analyses From Phase IIb Trial of MIN-101 in Schizophrenia Underscore Benefit in Multiple Measurements of Cognitive Function 154
Other Significant Developments 155
Oct 09, 2018: Astellas, Mitsubishi Tanabe Pharma, and Daiichi Sankyo announce second public recruitment offering of “Joinus”, a joint research program to discover new drugs using drug-repositioning compound library 155
Sep 26, 2018: Mitsubishi Tanabe Pharma announce company name changes of our oversea subsidiaries 156
Jul 02, 2018: Mitsubishi Tanabe Pharma and Osaka University co-found the “Department of Neuro-Medical Science” 157
Mar 06, 2018: Mitsubishi Tanabe Pharma Announces Singapore Subsidiary Name Change 158
Apr 17, 2017: Notice regarding overseas subsidiary MT Pharma Strengthening business development in the ASEAN region 159
Apr 17, 2017: Notice regarding overseas subsidiary MT Pharma (Thailand) Strengthening business development in the ASEAN region 160
Appendix 161
Methodology 161
About GlobalData 161
Contact Us 161
Disclaimer 161
Mitsubishi Tanabe Pharma Corp, Pharmaceuticals & Healthcare, Key Facts, 2018 2
Mitsubishi Tanabe Pharma Corp, Pharmaceuticals & Healthcare, Deals By Year, 2012 to YTD 2018 9
Mitsubishi Tanabe Pharma Corp, Pharmaceuticals & Healthcare Deals By Type, 2012 to YTD 2018 10
Mitsubishi Tanabe Pharma Corp, Pharmaceuticals & Healthcare, Deals By Region, 2012 to YTD 2018 11
Mitsubishi Tanabe Pharma Corp, Deals By Therapy Area, 2012 to YTD 2018 12
Mitsubishi Tanabe Pharma Corp, Medical Devices Deals, 2012 to YTD 2018 14
Mitsubishi Tanabe Pharma Corp, Pharmaceuticals & Healthcare, Deals Summary, 2012 to YTD 2018 15
QurAlis Raises Funds through Seed Financing 22
Ribometrix Raises USD7.5 Million in Seed Financing 23
Forge Therapeutics Raises USD15 million in Series A Financing 24
Rigontec Raises Additional USD16.7 Million in Series A Financing 25
miRagen Therapeutics Raises USD41 Million in Series C Financing 27
Thrasos Therapeutics Raises USD21 Million in Series D Financing 29
NeuroDerm Raises USD16 Million in Venture Financing 31
Covagen Raises US$50.3 Million In Series B Financing 32
F-Star Alpha Raises US$13 Million In Series A Financing 34
Thrasos Therapeutics Raises US$35 Million In Venture Financing 35
Genocea Biosciences Raises US$30 Million In Series C Financing 37
GenKyoTex Raises US$26 Million In Extended Series C Financing 39
Mitsubishi Tanabe Pharma and Osaka University Enter into Agreement 41
Mitsubishi Tanabe Pharma and Hitachi Enter into Agreement 42
Dyadic International Enters into Research Agreement with Mitsubishi Tanabe Pharma 43
AvantGen Partners with Tanabe Research Laboratories USA 44
Mitsubishi Tanabe Pharma, Order made Medical Research and Trans Chromosomics Form Partnership 45
Clinigen Enters into Distribution Agreement with Mitsubishi Tanabe Pharma 46
Mitsubishi Tanabe Pharma Forms Joint Venture with Research Foundation for Microbial Diseases of Osaka University 47
Mitsubishi Tanabe Pharma Expands Co-Promotion Agreement with Janssen Pharma 48
Takeda Pharma and Shionogi Enter into Research Agreement with Sumitomo Dainippon Pharma, Ono Pharma and Mitsubishi Tanabe Pharma 49
Mitsubishi Tanabe Pharma Enters into Research Agreement with Medicine for Malaria Venture 51
Teikoku Seiyaku Enters into Agreement with Mitsubishi Tanabe Pharma 52
Sun Pharma Enters into Distribution Agreement with Mitsubishi Tanabe Pharma 53
Mitsubishi Tanabe Pharma Enters into Distribution Agreement with Janssen Biotech 54
Akebia Therapeutics Enters into Agreement with Mitsubishi Tanabe Pharma 55
Medicago Enters into Contract with Public Health Agency of Canada 56
Regeneron Pharma Enters into Agreement with Mitsubishi Tanabe Pharma 57
Cardiome Pharma Enters into Agreement with Mitsubishi Tanabe Pharma Europe 58
Mitsubishi Tanabe Enters into Co-Promotion Agreement with Johnson & Johnson K.K. 59
Medicago Enters into Agreement with University of Cape Town 60
AstraZeneca Enters into Research Agreement with Mitsubishi Tanabe 61
AnGes MG Enters Into Co-Marketing Agreement With Mitsubishi Tanabe Pharma For Collategene 62
Medicago Enters Into Co-Development Agreement With A Global Pharma Company 63
Medicago Enters Into Co-Development Agreement With Mitsubishi Tanabe Pharma For Vaccines 64
Mitsubishi Tanabe Pharma Expands its Co-Marketing Agreement with Daiichi Sankyo for MP-513 And TA-7284 65
Medicago Enters Into Co-Development Agreement With Cellectis 66
Aquestive Therapeutics Enters into Licensing Agreement with Mitsubishi Tanabe Pharma 67
Mitsubishi Tanabe Pharma to Terminate Licensing Agreement with Kolon Life Science 68
Menarini Enters into Licensing Agreement with Mitsubishi Tanabe Pharma for Spedra 69
Tanabe Research Labs Enters into a Licensing Agreement with MedImmune 70
AnGes Enters into Licensing Agreement with Mitsubishi Tanabe Pharma 71
Neurocrine Biosciences Enters into Licensing Agreement with Mitsubishi Tanabe Pharma 72
Covagen Enters Into Licensing Agreement With Mitsubishi Tanabe Pharma And Tanabe Research Labs 73
Medicago Enters Into Licensing Agreement With Philip Morris Products For Influenza Vaccines 75
Philip Morris Products Enters Into Licensing Agreement With Medicago For Protein Development Technologies 76
Nuron Biotech Enters Into Licensing Agreement With Mitsubishi Tanabe For HibTITER 77
Covagen Expands Licensing Agreement With Mitsubishi Tanabe Pharma And Tanabe Research Labs 78
Immune Design And Medicago Enter Into Licensing Agreement To Develop Influenza Vaccines 80
Dezima Pharma Enters Into Licensing Agreement With Mitsubishi Tanabe Pharma For DEZ-001 81
miRagen Therapeutics Raises USD40.7 Million in Private Placement of Shares 82
NeuroDerm Completes Underwriters Exercise of Over-Allotment Option of Public Offering for USD86.3 Million 84
NeuroDerm Raises USD77 Million in Public Offering of Shares 86
NeuroDerm Raises USD45 Million in IPO 88
Medicago Announces Private Placement Of Common Stock For US$3.4 Million 90
Sawai Pharma to Acquire Kashima Plant from Mitsubishi Tanabe Pharma Factory for USD39.3 Million 91
Mitsubishi Tanabe Pharma Acquires Stelic Institute 92
Merck Acquires Rigontec 93
Mitsubishi Tanabe Pharma Acquires Neuroderm for USD1.1 Billion 95
Nipro Acquires Tanabe Seiyaku Hanbai from Mitsubishi Tanabe Pharma 97
CMIC Holdings Acquires Pharma Company from Mitsubishi Tanabe Pharma for USD32.2 Million 98
Medicago Completes Divestment Of 53.9% Stake To Mitsubishi Tanabe Pharma For US$ 172 Million In Going Private Transaction 99
Opko Health Completes Acquisition Of Cytochroma For Up To US$290 Million 101
Mitsubishi Tanabe To Acquire Remaining 49% Stake In Bipha From Nipro 103
Shire Completes Acquisition of Ferrokin Biosciences For Up To US$320 Million 104
Mitsubishi Tanabe Pharma Corp, Key Competitors 106
Mitsubishi Tanabe Pharma Corp, Key Employees 107
Mitsubishi Tanabe Pharma Corp, Other Locations 108
Mitsubishi Tanabe Pharma Corp, Subsidiaries 109
Mitsubishi Tanabe Pharma Corp, Joint Venture 110
List of Figures
Mitsubishi Tanabe Pharma Corp, Pharmaceuticals & Healthcare, Deals by Type, 2012 to YTD 2018 2
Mitsubishi Tanabe Pharma Corp, Pharmaceuticals & Healthcare, Deals By Year, 2012 to YTD 2018 2
Mitsubishi Tanabe Pharma Corp, Pharmaceuticals & Healthcare, Deals By Region, 2012 to YTD 2018 2
Mitsubishi Tanabe Pharma Corp, Pharmaceuticals & Healthcare, Deals By Therapy Area, 2012 to YTD 2018 2
Mitsubishi Tanabe Pharma Corp, Pharmaceuticals & Healthcare, Deals By Year, 2012 to YTD 2018 9
Mitsubishi Tanabe Pharma Corp, Pharmaceuticals & Healthcare, Deals by Type, 2012 to YTD 2018 10
Mitsubishi Tanabe Pharma Corp, Pharmaceuticals & Healthcare, Deals By Region, 2012 to YTD 2018 11
Mitsubishi Tanabe Pharma Corp, Pharmaceuticals & Healthcare, Deals By Therapy Area, 2012 to YTD 2018 12
Mitsubishi Tanabe Pharma Corp, Medical Devices Deals, 2012 to YTD 2018 14