Table of Contents
Table of Contents 3
List of Tables 6
List of Figures 7
Horizon Discovery Group Plc, Pharmaceuticals & Healthcare, Deals By Year, 2012 to YTD 2018 8
Horizon Discovery Group Plc, Pharmaceuticals & Healthcare Deals By Type, 2012 to YTD 2018 9
Horizon Discovery Group Plc, Pharmaceuticals & Healthcare, Deals By Region, 2012 to YTD 2018 10
Horizon Discovery Group Plc, Pharmaceuticals & Healthcare, Deals By Therapy Area, 2012 to YTD 2018 11
Horizon Discovery Group Plc, Medical Devices Deals, 2012 to YTD 2018 12
Horizon Discovery Group Plc, Pharmaceuticals & Healthcare, Deals Summary, 2012 to YTD 2018 13
Horizon Discovery Group Plc, Pharmaceuticals & Healthcare, Deal Details 17
Asset Purchase 17
Horizon Discovery Completes Acquisition of Combination High Throughput Screening from Zalicus 17
Venture Financing 18
Horizon Discovery Raises US$10.5 Million In Final Closing Of Series C Financing 18
Private Equity 20
ValueAct Capital Acquires Additional Stake in Horizon Discovery Group from Woodford Investment Management 20
Partnerships 21
Horizon Discovery Enters into Licensing Agreement for Transposon Based Technology Platform 21
Horizon Discovery Enters Into Licensing Agreement With ATCC 22
Celyad Enters into Agreement with Horizon Discovery 23
Horizon Discovery Enters into Partnership 24
Horizon Discovery Enters into Co-Development Agreement with Roche Diagnostics 25
Horizon Discovery Enters into Research Agreement with Solentim 26
Horizon Discovery Enters into Agreement with Fulcrum Therapeutics 27
Horizon Discovery Enters into Agreement with Ubiquigent 28
Horizon Discovery Forms Joint Venture with Centauri Therapeutics 29
Horizon Discovery Partners with Axol Bioscience 30
Horizon Discovery Enters into Agreement with Swift Biosciences 31
Horizon Discovery Enters into Research Agreement with Redx Pharma 32
Horizon Discovery Enters into Co-Development Agreement with DefiniGEN 33
CareDx Enters into Co-Development Agreement with Horizon Discovery 34
Horizon Discovery Enters into Agreement with Thermo Fisher Scientific 35
Horizon Discovery Enters Into Marketing Agreement With Thermo Fisher 36
Horizon Discovery Enters into Distribution Agreement with Haplogen Genomics 37
Horizon Discovery Enters into Development and Commercialization Agreement with Otsuka Pharma 38
Horizon Discovery Enters Into Co-Development Agreement With Desktop Genetics 39
Crown Bioscience Enters Into Agreement With Horizon Discovery To Develop In Vivo Models For Drug Discovery 40
Horizon Discovery Enters Into R&D Agreement With UCL Institute of Neurology For rAAV-mediated Genome Editing 41
Crown Bioscience Enters Into Co-Development Agreement With Horizon Discovery 42
Horizon Discovery Enters Into Agreement With Domainex To Support Oncology Program 43
Horizon Discovery Enters Into Co-Development Agreement With Bayer Pharma For Human Isogenic Cell Lines 44
Horizon Discovery Enters Into Co-Development Agreement With H3 Biomedicine 45
Licensing Agreements 46
Cytovance Biologics Enters into Licensing Agreement with Horizon Discovery 46
Horizon Discovery Enters into Licensing Agreement with US Immuno-Oncology Company 47
ATUM Enters into Licensing Agreement with Horizon Discovery 48
Horizon Discovery Enters into Licensing Agreement with ATUM 49
Horizon Discovery Group Enters into Licensing Agreement with AmplyCell 50
Horizon Discovery Enters into Licensing Agreement with Wistar Institute 51
Horizon Discovery Enters into Licensing Agreement with Servier Lab 52
LakePharma Enters into Licensing Agreement with Horizon Discovery 53
Abcam Enters into Licensing Agreement with Horizon Discovery 54
Horizon Discovery Extends Licensing Agreement with ERS Genomics 55
Horizon Discovery And AstraZeneca Enter Into Licensing Agreement To Develop Cancer Therapies 56
Horizon Discovery Group Enters into Licensing Agreement 58
Horizon Discovery Enters into Licensing Agreement with ProteoNic 59
Horizon Discovery Enters into Licensing Agreement with Stanford University 60
Horizon Discovery Enters into Licensing Agreement with Broad Institute for Crispr Gene Editing System 61
Horizon Discovery Enters Into Licensing Agreement With AstraZeneca 62
Horizon Discovery Enters Into Licensing Agreement With Harvard University For Crispr Gene Editing Technology 63
Sigma-Aldrich Enters Into Licensing Agreement With Horizon Discovery For CompoZr Zinc Finger Nuclease Technology 64
NIH Center for Regenerative Medicine Enters Into Licensing Agreement With Horizon Discovery For Genesis Technology 65
Horizon Discovery Enters Into Licensing Agreement With Rosalind Franklin University of Medicine and Science 66
Equity Offering 67
Horizon Discovery Raises USD104.6 million in Private Placement of Shares 67
Horizon Discovery Raises USD38.5 Million in Private Placement of Shares 68
Horizon Discovery Completes IPO For US$66.7 Million 69
Acquisition 71
Horizon Discovery Acquires GE Healthcare Dharmacon from General Electric for USD85 Million 71
Horizon Discovery Acquires Haplogen Genomics for USD15 Million 73
Horizon Discovery Acquires Sage Labs for USD48 Million 74
Horizon Discovery Group Plc – Key Competitors 75
Horizon Discovery Group Plc – Key Employees 76
Horizon Discovery Group Plc – Locations And Subsidiaries 77
Head Office 77
Other Locations & Subsidiaries 77
Joint Venture 78
Recent Developments 79
Financial Announcements 79
Sep 17, 2018: HORIZON DISCOVERY GROUP announce interim results for the six months ended 30 June 2018 79
May 08, 2018: Horizon Discovery Group: Preliminary Results for the Year Ended 31 December 2017 84
Sep 26, 2017: Horizon Discovery Group: Interim Results For The Six Months Ended 30 June 2017 85
May 30, 2017: Horizon Discovery Group: Preliminary Results for the Year Ended 31 December 2016 91
Corporate Communications 92
May 17, 2018: Horizon Discovery: Board Change 92
May 08, 2018: Horizon Discovery appoints Terry Pizzie as Chief Executive Officer 93
Mar 02, 2018: Horizon Discovery Group: Board Change 94
Feb 20, 2018: Horizon Discovery Announces Leadership Changes 95
Legal and Regulatory 96
Jul 03, 2017: Horizon Discovery announces inclusion of its Reference Standards in successful FDA approval of an oncology companion diagnostic test with leading next generation sequencing company 96
Government and Public Interest 97
Jul 17, 2017: Sphere Fluidics and Partners Win Major InnovateUK Grant to Develop the World’s First Desktop Genome Editing System 97
May 22, 2017: Horizon Discovery Announces New Gene Editing Technology Platform for Research and Therapeutic Applications 98
Product News 99
Nov 14, 2017: Horizon Discovery’s Dharmacon introduces Edit-R CRISPRa reagent platform for genome-wide CRISPR activation 99
Aug 01, 2017: Horizon Discovery announces release of high quality, well annotated CHO genome sequence to drive innovation in bioproduction 100
May 26, 2017: Horizon Discovery introduces four BRAF resistant melanoma PDX models 102
Mar 26, 2018: Horizon Discovery introduces whole human genome arrayed libraries to support CRISPR activation screening 103
Other Significant Developments 104
Sep 14, 2018: Horizon Discovery Edit-R crRNA libraries adopted by AstraZeneca as part of its functional genomics discovery platform 104
Mar 21, 2018: Horizon Discovery’s Bioproduction cell line used as part of a successful drug (IND) filing 105
Sep 18, 2017: Horizon Discovery announces launch of Genome-Wide CRISPRi and CRISPRa Screening Services 106
May 09, 2017: Horizon Discovery Announces Update on its Immuno-Oncology Platform including Strong Uptake of Product and Service Offerings 107
Jan 24, 2017: Horizon Discovery Group: Trading Update 108
Jan 13, 2017: International Trade Minister Greg Hands visits fast-growing Cambridge life sciences company 109
Appendix 110
Methodology 110
About GlobalData 110
Contact Us 110
Disclaimer 110
Horizon Discovery Group Plc, Pharmaceuticals & Healthcare, Key Facts, 2017 2
Horizon Discovery Group Plc, Pharmaceuticals & Healthcare, Deals By Year, 2012 to YTD 2018 8
Horizon Discovery Group Plc, Pharmaceuticals & Healthcare Deals By Type, 2012 to YTD 2018 9
Horizon Discovery Group Plc, Pharmaceuticals & Healthcare, Deals By Region, 2012 to YTD 2018 10
Horizon Discovery Group Plc, Deals By Therapy Area, 2012 to YTD 2018 11
Horizon Discovery Group Plc, Medical Devices Deals, 2012 to YTD 2018 12
Horizon Discovery Group Plc, Pharmaceuticals & Healthcare, Deals Summary, 2012 to YTD 2018 13
Horizon Discovery Completes Acquisition of Combination High Throughput Screening from Zalicus 17
Horizon Discovery Raises US$10.5 Million In Final Closing Of Series C Financing 18
ValueAct Capital Acquires Additional Stake in Horizon Discovery Group from Woodford Investment Management 20
Horizon Discovery Enters into Licensing Agreement for Transposon Based Technology Platform 21
Horizon Discovery Enters Into Licensing Agreement With ATCC 22
Celyad Enters into Agreement with Horizon Discovery 23
Horizon Discovery Enters into Partnership 24
Horizon Discovery Enters into Co-Development Agreement with Roche Diagnostics 25
Horizon Discovery Enters into Research Agreement with Solentim 26
Horizon Discovery Enters into Agreement with Fulcrum Therapeutics 27
Horizon Discovery Enters into Agreement with Ubiquigent 28
Horizon Discovery Forms Joint Venture with Centauri Therapeutics 29
Horizon Discovery Partners with Axol Bioscience 30
Horizon Discovery Enters into Agreement with Swift Biosciences 31
Horizon Discovery Enters into Research Agreement with Redx Pharma 32
Horizon Discovery Enters into Co-Development Agreement with DefiniGEN 33
CareDx Enters into Co-Development Agreement with Horizon Discovery 34
Horizon Discovery Enters into Agreement with Thermo Fisher Scientific 35
Horizon Discovery Enters Into Marketing Agreement With Thermo Fisher 36
Horizon Discovery Enters into Distribution Agreement with Haplogen Genomics 37
Horizon Discovery Enters into Development and Commercialization Agreement with Otsuka Pharma 38
Horizon Discovery Enters Into Co-Development Agreement With Desktop Genetics 39
Crown Bioscience Enters Into Agreement With Horizon Discovery To Develop In Vivo Models For Drug Discovery 40
Horizon Discovery Enters Into R&D Agreement With UCL Institute of Neurology For rAAV-mediated Genome Editing 41
Crown Bioscience Enters Into Co-Development Agreement With Horizon Discovery 42
Horizon Discovery Enters Into Agreement With Domainex To Support Oncology Program 43
Horizon Discovery Enters Into Co-Development Agreement With Bayer Pharma For Human Isogenic Cell Lines 44
Horizon Discovery Enters Into Co-Development Agreement With H3 Biomedicine 45
Cytovance Biologics Enters into Licensing Agreement with Horizon Discovery 46
Horizon Discovery Enters into Licensing Agreement with US Immuno-Oncology Company 47
ATUM Enters into Licensing Agreement with Horizon Discovery 48
Horizon Discovery Enters into Licensing Agreement with ATUM 49
Horizon Discovery Group Enters into Licensing Agreement with AmplyCell 50
Horizon Discovery Enters into Licensing Agreement with Wistar Institute 51
Horizon Discovery Enters into Licensing Agreement with Servier Lab 52
LakePharma Enters into Licensing Agreement with Horizon Discovery 53
Abcam Enters into Licensing Agreement with Horizon Discovery 54
Horizon Discovery Extends Licensing Agreement with ERS Genomics 55
Horizon Discovery And AstraZeneca Enter Into Licensing Agreement To Develop Cancer Therapies 56
Horizon Discovery Group Enters into Licensing Agreement 58
Horizon Discovery Enters into Licensing Agreement with ProteoNic 59
Horizon Discovery Enters into Licensing Agreement with Stanford University 60
Horizon Discovery Enters into Licensing Agreement with Broad Institute for Crispr Gene Editing System 61
Horizon Discovery Enters Into Licensing Agreement With AstraZeneca 62
Horizon Discovery Enters Into Licensing Agreement With Harvard University For Crispr Gene Editing Technology 63
Sigma-Aldrich Enters Into Licensing Agreement With Horizon Discovery For CompoZr Zinc Finger Nuclease Technology 64
NIH Center for Regenerative Medicine Enters Into Licensing Agreement With Horizon Discovery For Genesis Technology 65
Horizon Discovery Enters Into Licensing Agreement With Rosalind Franklin University of Medicine and Science 66
Horizon Discovery Raises USD104.6 million in Private Placement of Shares 67
Horizon Discovery Raises USD38.5 Million in Private Placement of Shares 68
Horizon Discovery Completes IPO For US$66.7 Million 69
Horizon Discovery Acquires GE Healthcare Dharmacon from General Electric for USD85 Million 71
Horizon Discovery Acquires Haplogen Genomics for USD15 Million 73
Horizon Discovery Acquires Sage Labs for USD48 Million 74
Horizon Discovery Group Plc, Key Competitors 75
Horizon Discovery Group Plc, Key Employees 76
Horizon Discovery Group Plc, Other Locations 77
Horizon Discovery Group Plc, Subsidiaries 77
Horizon Discovery Group Plc, Joint Venture 78
List of Figures
Horizon Discovery Group Plc, Pharmaceuticals & Healthcare, Deals by Type, 2012 to YTD 2018 2
Horizon Discovery Group Plc, Pharmaceuticals & Healthcare, Deals By Year, 2012 to YTD 2018 2
Horizon Discovery Group Plc, Pharmaceuticals & Healthcare, Deals By Region, 2012 to YTD 2018 2
Horizon Discovery Group Plc, Pharmaceuticals & Healthcare, Deals By Therapy Area, 2012 to YTD 2018 2
Horizon Discovery Group Plc, Pharmaceuticals & Healthcare, Deals By Year, 2012 to YTD 2018 8
Horizon Discovery Group Plc, Pharmaceuticals & Healthcare, Deals by Type, 2012 to YTD 2018 9
Horizon Discovery Group Plc, Pharmaceuticals & Healthcare, Deals By Region, 2012 to YTD 2018 10
Horizon Discovery Group Plc, Pharmaceuticals & Healthcare, Deals By Therapy Area, 2012 to YTD 2018 11
Horizon Discovery Group Plc, Medical Devices Deals, 2012 to YTD 2018 12